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活动日期： 2024年8月7日

Below are the speakers' details: 

Prof Pan Tingrui

Chair Professor of USTC and SIAR

Fellow of the American Institute for Medical and Biological Engineering

Royal Society of Chemistry RSC

Yangtze River Scholar Chair Professor by the Ministry of Education

Talk title: Iontronic Intelligence-Enabled Next-Gen Medical Wearables

Biography: Professor Tingrui Pan is a fellow of the American Institute for Medical and Biological Engineering (AIMBE) and the Royal Society of Chemistry RSC, and a Yangtze River Scholar Chair Professor by the Ministry of Education of the People’s Republic of China. He is currently a Chair Professor of USTC and SIAR. Before returning to China, Prof. Pan was a tenured Full Professor of the Department of Biomedical Engineering at the University of California, Davis 

Continuous hemodynamic monitoring in a wearable means can play a crucial role in managing hypertension and preventing catastrophic cardiovascular events. In this talk, we have described the first wearable tonometric device, referred to as flexible adaptive sensing tonometry (FAST), capable of continuous and accurate monitoring of hemodynamic parameters with the medical-grade precision.

In particular, the FAST system integrates an array of highly sensitive and highly flexible iontronic sensors (FITS) with 1mm spatial resolution and a closed-loop motion system. The flexible tonometric architecture enables highly adaptive and conformable attachment to human skin while simplifying the process to determine the radial arterial position, leading to a wearable watch device with an efficient pulse wave acquisition. Importantly, a self-calibration algorithm has been incorporated during the applanation process, from which the intra-arterial blood pressure wave can be continuously predicted within a medical-grade precision, and subsequently, multi-parametric hemodynamic analysis can be performed in real-time.

Experimental validations on both benches and health volunteers have demonstrated that the FAST measurements are all within the required accuracy of the clinical standards for continuous pulse wave assessments, blood pressure monitoring as well as other key hemodynamic parameter evaluations. Therefore, the FAST system, by integrating the flexible iontronic sensing array, provides a real-time, medical-grade hemodynamic monitoring solution in a continuously wearable manner, from which remote patient-centered monitoring can be delivered with both medical precision and convenience.